Custom Supplement Boxes
All custom Supplement Boxes you need for your products
FREE Shipping All Across the USA No minimums, no hidden freight fees — to all 50 states.
FREE 3D Design Tool Build & preview your box online before you order.
FREE Design Support Our US team perfects your artwork & 3D mockup.
Small custom supplement boxes built for US vitamin, nutraceutical, and wellness brands that need retail-ready cartons without an enterprise order. We print your outer cartons on SBS or kraft folding board — designed to accommodate the Supplement Facts panel, US contact info, batch and lot fields, and a scannable barcode — from 100 units with no plate, die, or setup fees. Ships flat across the USA to keep freight cheap, with free US shipping, free Pantone matching, a free 3D mockup, and a free custom sample refunded on your production order. Typical per-unit lands around $2.30-$2.80 at 250 qty and drops toward $1.90 at 500+.
For US supplement, vitamin, nutraceutical, and wellness brands — indie launches and growth-stage founders alike — who need FDA-panel-ready cartons at low MOQ.
About Custom Supplement Boxes
Cartons designed around the Supplement Facts panel
A supplement carton is a regulatory surface first and a brand surface second. FDA rules (21 CFR 101.36) require a Supplement Facts panel with serving size, servings per container, active and other ingredients, and %DV where relevant — and it has to be legible at 6-8pt type in a specific format. The panel needs real estate, and it needs a stock that holds fine type without ink spread. We design cartons around your actual product and dosage layout, not a stock template — so your Supplement Facts, Other Ingredients, US manufacturer or distributor address (21 CFR 101.5), lot and expiration fields, and barcode all fit legibly with room for your brand to still lead the front panel. We print the approved artwork.
Small custom supplement boxes by product format
Every supplement format has a different structural fit. Start with the box built for your delivery form:
- Vitamin bottle outer cartons — vitamin bottle boxes for HDPE, glass, or PET rounds in 30/60/90/120-count.
- Softgels & capsules — softgel boxes for fish oil, vitamin D, omega, CoQ10; capsule boxes for herbal, adaptogen, and single-ingredient hard-shell lines.
- Gummies — gummy supplement boxes distinct from candy or CBD gummy formats.
- Tinctures & droppers — tincture boxes for herbal, botanical, and mushroom extracts, and dropper bottle boxes for essential oils and functional serums.
- Powders — protein powder boxes for outer cartons on tubs, sachets, and variety packs.
- Broad categories — nutraceutical boxes for functional-food crossovers and dietary supplement boxes when the SKU doesn't fit one clean lane.
Structures we print most for supplement brands
- Reverse and straight tuck-end cartons — the workhorse for bottle and softgel outer cartons; ships flat, opens fast at the pack station.
- Auto-bottom folding cartons — for heavier bottles (60+ count) where the base has to support real weight without collapse.
- Sleeve-and-tray — for gift sets, sample kits, and starter bundles.
- Window boxes — when you want to show the gummy color, powder texture, or capsule count through a die-cut PET window.
Compliance content the carton must carry
We build your dieline with the space and legibility for every mandatory element, and lay it out cleanly for retail:
- Supplement Facts panel per 21 CFR 101.36 (serving size, servings per container, nutrient names and quantities, %DV, source ingredients where required)
- Statement of identity (product name and delivery form) on the principal display panel
- Net quantity of contents (count or weight)
- Ingredient statement — "Other Ingredients:" section for excipients, binders, and coatings
- Name and place of business — US manufacturer, packer, or distributor with a US address (21 CFR 101.5). If you're an imported-product brand, this address is what carries the compliance burden.
- Lot code, batch number, and expiration date fields (usually a blank print zone for hot-stamping)
- Scannable UPC/EAN barcode
- Any warning or allergen statements your formula requires
What we will NOT print: therapeutic disease claims ("cures", "treats", "prevents", "diagnoses"). FDA classifies those as drug claims and moves the product out of the supplement regulatory pathway. Structure/function claims ("supports immune function", "helps maintain healthy hair") are permitted when accompanied by the required disclaimer — we'll lay it out for you if it's in your approved copy.
Sustainability on supplement packaging
Wellness buyers read the box as closely as the ingredient panel. We print on recyclable SBS and FSC-certified stocks, offer unbleached kraft with a matte finish for clean-label lines, and right-size every dieline so you ship less air and less material. If recyclability or FSC is part of your brand promise, tell us and we'll spec a construction and finish that supports the claim.
Ships flat, low freight, US-shipped
Supplement cartons ship flat across the USA — you pay for cardboard, not for air. Free contiguous-US shipping on every order, runs starting at 100 units with no plate, die, or setup fees, and typical turnaround is 8-10 US business days from artwork approval. A free physical sample can be sent for large runs and its cost is refunded on your production order, so a $50-$100 sample never becomes a sunk cost.
Related packaging & guidance
- For OTC and pharmacy-adjacent products: medicine boxes.
- For CBD or hemp-derived wellness: start at the CBD boxes hub.
- For candy-format gummies (not supplement): gummies boxes.
Why US brands choose us for custom supplement boxes
Custom Box Printing manufactures custom supplement boxes from our US production facility, with free standard shipping anywhere in the contiguous United States and a 7–10 business day turnaround. We've printed custom supplement boxes for solo founders launching their first product line, growing direct-to-consumer brands placing 5,000-unit runs, and established retail brands with 50,000+ unit production schedules — and we treat all three the same: no minimums, free design support, no setup or die-plate charges, and a 3D digital mockup before anything goes to press.
Every custom supplement boxes order includes free in-house dieline and artwork support — our US-based designers will polish your existing files, or build a custom dieline from scratch to fit your exact product dimensions. We send you a 3D mockup to confirm look and proportions before production. For color-critical work, request a physical sample free — let’s talk about a customized sample so you can confirm the look before a full run.
Materials, print, and finish options
Folding cartonboard is the supplement standard. SBS (solid bleached sulfate, 14pt-18pt) is the everyday choice — a bright white surface that holds fine 6-8pt regulatory copy crisply and prints Pantone colors true across a product line. Unbleached kraft in the same weights suits clean-label, plant-based, and natural-wellness lines that want the honest, recyclable look. CCNB is the recycled-content option when sustainability is on the brand promise. Any of the three pairs with matte lamination for anti-glare readability on dense Supplement Facts panels, soft-touch for a premium feel, or spot UV and foil to lift the front-panel logo without crowding the required copy.
Available finishes include:
- Lamination: Gloss, matte, soft-touch, or velvet finish for a premium hand-feel.
- Foil stamping: Gold, silver, copper, or custom foil colors for high-visibility brand marks.
- Embossing & debossing: Tactile raised or recessed surface effects on logo or key artwork.
- Spot UV: Selective gloss coating that creates contrast against matte areas.
- Eco-friendly options: Recycled kraft, FSC-certified stocks, water-based inks, recyclable rigid constructions.
- Compliance: FDA food-safe inks; certified child-resistant constructions for CBD/cannabis where required.
If you're not sure which combination will work best for your custom supplement boxes, mention it in your quote request — our team will recommend the right material, print spec, and finish based on your product, budget, and brand positioning.
How to order your custom supplement boxes
- Request a quote — use the "Get Free Quote" button on this page, or call (855) 792-3890 (toll free). Tell us your box style, dimensions, quantity, material preferences, and any deadline.
- We respond within 1 business day with pricing, lead times, and material recommendations. No pressure, no commitment.
- Free design + 3D mockup — we build your dieline (or polish your existing artwork) and send you a 3D digital mockup to approve.
- Optional physical sample — request a free custom sample to hold the real box in hand — let’s talk it through.
- Production & free US shipping — once you approve, we print and ship in 7–10 business days, free anywhere in the United States.